Volume :
1
Issue :
4
Abstract :
The objective of this study was to verify the claims and to evaluate the anti-diabetic activity of the roots of Hygrophila spinosa, by preparing the various organic extracts and the resultant extracts are to be screened for the anti-diabetic activity to prove the claimed activity. The chloroform, ethyl acetate and alcohol extracts of Hygrophila spinosa, roots were prepared and subjected for phytochemical screening and tested for their anti-diabetic activity on alloxan-induced diabetic rats. Phytochemical screening showed positive test for steroids and/or triterpenoids (CHCl3 extract), steroids and/or triterpenoids and their glycosides (EtoAc extract), steroids and/or triterpenoids and their glycosides (EtOH extract). The ethyl acetate and ethanol have shown significant anti-diabetic activity at a dose of 200 mg/kg, p.o. The study results suggested that Hygrophila spinosa, roots possessed potential anti-diabetic activity.