Abstract :
Human platelets do not express any antigens of the Rhesus system. However, platelet concentrates contain the variable volume of contaminating RBCs, which may induce RhD alloimmunization when transfused in a RhD negative subject. Though low rate of anti-D alloimmunization related to platelet transfusion, the development of RhD and non-RhD antibodies cannot be ignored. Thus, transfusion practices could allow the transfusion of RhD positive platelet units to RhD negative patients, with the exception of females of childbearing age.
Keyword :
Platelet, Transfusion, Alloimmunization, Donor, Antibody, Antigen.