Abstract :
Recurrence of well differentiated thyroid carcinomas with anaplastic transformation has been a challenge to the clinicians and is life threatening to the patient. Transformation of papillary thyroid carcinoma to the anaplastic variant in the metastatic foci is very rare.We report a case of recurrent papillary thyroid carcinoma with anaplastic transformation metastasizing to larynx. The challenge for pathologists is to identify this transformation, so that treatment may be tailored appropriately.
Keyword :
Papillary thyroid carcinoma (PTC), Anaplastic thyroid carcinoma (ATC), Thyroglobulin -Tg, Radioactive iodine (RAI), Histopathological examination (HPE), Well Differentiated thyroid carcinomas (WDTC)