Volume :

6

Issue :

2

Abstract :

A simple, accurate, precise and economic spectrophotometric method has been developed for the determination of Gabapentin in their bulk powder and pharmaceutical dosage form. Gabapentin showed maximum absorbance at 216 nm with Methanol as solvent. Beer’s law was obeyed in the concentration range 10-60 μg/ml with regression coefficient of 0.999. The concentration of active component were then determined from the calibration curve obtained by measuring the amplitude at 216 nm for gabapentin. Accuracy and precision of the developed methods have been tested in addition recovery studies have been carried out in order to confirm their accuracy. The method was validated in terms of linearity, precision, accuracy (99.2-101.5%w/w) and specificity. This method is simple, precise, accurate, sensitive and reproducible and can be used for the routine quality control testing of the marketed formulations.