Article type :
Case Report
Author :
Surjeet Dwivedi, Rakesh Kumar Jha, Prasad V Jayaram, Prasad V Jayaram, Surjeet Dwivedi, Rakesh Kumar Jha, Prasad V Jayaram, Prasad V Jayaram
Volume :
7
Issue :
3
Abstract :
Though connective tissue disorders are known to be associated with a higher risk of lung malignancies, the occurrence of Systemic Lupus Erythematosus (SLE) with adeno-carcinoma lung is rare and restricted to only a few case reports. The understanding of the association between the two diseases is still in infancy. The association of malignancy with SLE has been attributed to factors such as the setting of chronic inflammation, use of immunosuppressive drugs and shared gene pathways. There is also overlap between some clinical and biochemical features of SLE and lung carcinoma which may affect diagnosis. However, there is no adverse effect of SLE on the prognosis of patients with adenocarcinoma lung and they benefit from timely intervention based on careful surveillance. We describe a case where a patient of SLE was incidentally detected to have a lung lesion during routine screening, which was found to be adenocarcinoma on investigation and managed successfully with lobectomy.
Keyword :
Adenocarcinoma, Systemic lupus erythematosus, Lung neoplasms, Connective tissue diseases