Abstract :
Background: In patients suffering from malignancies incidence of tuberculosis is highest in cases of
hematological malignancies in comparison to solid organ malignancies. 1 Despite the fact tuberculosis
remains under-diagnosed condition in hematological malignancies like acute leukemia and it may be a
cause of febrile neutropenia in these cases. Rescheduling and/or alterations in therapies are required in
these cases. 2
Case History: A 16year old male diagnosed as case of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1
was on therapy after 6 weeks interval from initiation of therapy he presented with fever, weakness,
lymphadenopathy and cough with expectoration since 15 days.
Keyword :
Acute leukemia, Tuberculosis, AML with t(8 21)(q22;q22)RUNX1-RUNX1T1, Acute myeloid leukemia, Therapy.