Abstract :
The planar structure and the fluorescence nature of the acridone nucleus has been extensively exploited in
numerous biological systems. From the monitoring of the biological processes to the designing of the biologically
active compounds the acridone nucleus has played a pivotal role. Especially in the development of anticancer
therapy, the commend ability of the acridone nucleus is numerous. The acridone nucleus is known to halt DNA
duplication as well as arrests the cell cycle. Besides, the acridone nucleus also finds implications in the development
of the oxidative stress therapy to cure cancer. Being a highly conjugated system, there is delocalization of the free
electrons in the acridone nucleus which helps in the creation of oxidative stress as well as scavenging the free
radicals in the cells. The current review comprehensively deals with the various biological applications of the
acridone nucleus.
Keyword :
Acridone, Acridine