Abstract :
Aim:The current study was aimed to identify drug related problems among chronic kidney disease patients who were
diagnosed with end stage renal disease.
Methodology:A retrospective study was conducted on hospitalized patients diagnosed with end stage renal disease. Six
months patients profile data was collected from the record room of the tertiary care hospital (Government Provincial
Sandeman Hospital Quetta). Patients’ demographic information and prescribed drugs were collected through a pre
validated data collection form were analyzed for the identification of drug therapy problems. Statistical Package for Social
Sciences software was used for data analysis and data was presented descriptively.
Results:A total of 202 patients profiles were assessed out of which 177 (87.62 %) were males and 25 (12.38%) were females.
Average age found in the study was 42+15 years. The total number of drugs prescribed to the patients was 946 with the
average of 5 drugs per prescription. Overall 501 drug related problems were identified with the average of 2.4 problems per
prescription. The most commonly reported drug related problems were inappropriate dosage (146, 72.3%), drug
interactions (120, 54.4%), contraindication (56, 27.7%), treatment duplicity (43, 21.2%), need of additional treatment (40,
19.8%), economic reasons (23, 11.3), adverse drug reactions (18, 8.9%), side effects (17, 8.4%) and other medication being
more effective (13, 6.43%).
Conclusion:Drug therapy problems found per prescription were quite high that needs urgent attention. Within this context,
the role of clinical pharmacist should be highlighted to identify, resolve and prevent drug therapy problems especially in
such critical area of care .
Keyword :
Drug therapy problems, chronic kidney disease patients, tertiary care hospital, Quetta, Pakistan.