Abstract :
Background and Objective: Ovarian Hyperstimulation Syndrome (OHSS) is the most common iatrogenic and potentially lethal
adverse effect of ovarian induction in Assisted Reproductive Technologies (ART). Recently, anti-mullerian hormone (AMH) is
considered as risk factor for ovarian hyper-response in addition to estradiol in patients undergoing in vitro fertilization (IVF).
The present study was aimed to assess the accuracy of anti-mullerian hormone (AMH) and Estradiol in the incidence of OHSS.
Materials and Methods: This is a retrospective diagnostic test study and all infertile women who undergone IVF and ICSI
procedures between 2012-2013, who were 4.2, the PPV of estradiol rose to 49.5%.
Conclusion: Estradiol showed better sensitivity and specificity than other markers for prediction of OHSS. Classification of
patients on the basis of AMH can lead to a higher sensitivity and specificity for estradiol with a higher cut-off value in OHSS
prediction in patients with AMH≤ 4.2
Keyword :
Ovarian Hyperstimulation Syndrome, Anti-Mullerian Hormone, Estradiol.