Article PDF :

Veiw Full Text PDF

Article type :

Review Article

Author :

Vincy Antony, Anthony George, Prathapan Parayaruthottam, Muhamed Shaloob, Vincy Antony, Anthony George, Prathapan Parayaruthottam, Muhamed Shaloob, Vincy Antony, Anthony George, Prathapan Parayaruthottam, Muhamed Shaloob, Vincy Antony, Anthony George, Prathapan Parayaruthottam, Muhamed Shaloob

Volume :

9

Issue :

4

Abstract :

Objectives: Orthodontic root resorption is a significant concern during orthodontic treatment, and can range from mild (0.4-1.5mm) to severe root resorption (>4mm). Recent studies have suggested that Dentin Sialo phosphoprotein (DSPP) may also be associated with the development and progress of orthodontic root resorption. The current systematic review's objective is to investigate the data currently available about the quantification of DSPP in patients who have orthodontic root resorption.Materials and Methods: Using both manual and computer databases, a thorough literature search was carried out to find pertinent papers. Primary research studies that explored the association between DSPP expression and orthodontic root resorption in human subjects had been included in the inclusion criteria. The extraction of data and quality appraisal were performed according to established guidelines. A qualitative synthesis of the findings was performed due to variations in study designs and methodologies.Results: During the initial search, 1192 records were found in total. After the screening procedure, thirty-three papers were chosen for full-text review. Both exclusion and inclusion criteria were used, and twelve studies were ultimately included in this systematic review. Study design, sample size, measuring techniques, and outcome measures varied between the research. DSPP expression and root resorption may be positively correlated, according to some research, although other investigations produced contradictory or equivocal findings.Conclusions: This systematic review draws attention to the discrepancies in the literature that currently exist on the association between orthodontic root resorption and dentin sialophosphoprotein expression. Methodological differences and limitations across the studies contribute to the inconsistency in findings. The role of DSPP as a predictive marker for root resorption in orthodontic treatment has to be clarified by more studies using bigger sample sizes and standard methods.