Abstract :
Background: IgE is a major contributing factor for the development of bronchial hyper responsiveness in asthmatics. Serum IgE levels also shows association with degree of airflow obstruction. Therefore, a study was undertaken to estimate the serum IgE level in bronchial asthma patients, and to correlate the severity of airway obstruction with serum IgE level in bronchial asthma patients. A total of 75 cases in the age group of 21-60 years, of Tertiary care Hospital, Madagadipet, Puducherry-India was included in the study. Spirometry with reversibility testing was done in all cases. Serum IgE level was estimated using Quantia IgE, which is a turbid metric immunoassay. Patients with bronchial asthma had elevated serum IgE, which increased with increase in the severity of airflow obstruction and it was found to be statistically significant (p
Keyword :
Allergic asthma-; Serum IgE; Severity of obstruction; Spirometry-IgE therapy