A study of virulence factors of E. coli strains isolated from cases of urinary tract infection


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Article type :

Original Article

Author :

Krati Varshney, Sanjeev Dimri*

Volume :

8

Issue :

2

Abstract :

Aim: The aim of this study was to demonstrate virulence factors namely adhesins, hemolysin and cell surface hydrophobicity of E. coli strains isolated from cases of urinary tract infection. Materials and Methods: A total of 210 E. coli strains were isolated from 602 culture positive cases of urinary tract infections. UPEC strains were screened for virulence factors namely hemolysin, hemagglutination and cell surface hydrophobicity by recommended methods. Result: Out of 210 E. coli strains tested, 70 (33.34%) were hemolytic, 94 (44.76%) showed hemagglutination and 46 (21.90%) were cell surface hydrophobicity positive. Conclusion: Our study shows that a large number of uropathogenic E. coli strains had one or more virulence factors. The methods of detection of above-mentioned virulence factors are reasonably easy and screening them in a clinical microbiology laboratory is a worthwhile exercise.

Keyword :

UTI, E coli, UPEC, MRHA, MSHA, Hemolysin, CSH.
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