Abstract :
Introduction: The prevalence of the ischemic heart diseases is increasing globally which is also associated
with high prevalence as well mortality. Associated comorbidities like diabetes and hypertension increases
the associated mortality and morbidity. Atherosclerosis of the coronaries and resultant narrowing of the
lumen is the associated underlying cause.
Aims and Objective: The aim of the present study was to study gross pathological changes in heart in
case of acute MI as well as the sex preponderance of the disease and other related factors.
Material and Methods: In this prospective study, conducted at the tertiary care government hospital, 35
cases of sudden death subsequent to acute myocardial infraction were enrolled. This study was conducted
during the period from April 2017 to July 2018. All the cases were studied for myocardial infraction and
its underlying pathological changes in the myocardium as well as the blockade of coronary arteries.
Results: A total of 35 subjects (20 M, 15 F), the mean age of the subjects was 55.02 years whereas the
maximum numbers of subjects were of 50-59 years of age. Majority of the subjects were found to follow
sedentary lifestyle. 28 subjects showed grade 2 and 6 cases showed grade 3 blockade in the right coronary
artery. In the left anterior descending artery: Out of 35 cases, 1 case showed grade 1 block, 25 cases showed
grade 2 blockages and 9 cases showed grade 3 blocks. The examination of aorta showed in 2 cases grade 1
block, in 20 cases grade 2 block and in 13 cases grade 3 block. 8 cases showed hemorrhagic myocardium.
Conclusion: It was concluded in the present study that the maximum incidence of MI was associated in the
age group of 50-59 years and it is associated with sedentary lifestyle. Males were more commonly affected
than females. Coronary atherosclerosis is one of the most common underlying cause, the right coronary
being the commonest artery involved.
Keyword :
Acute MI, Coronary arteries, Sudden death, Post mortem examination.