Volume :

6

Issue :

1

Abstract :

Gestational diabetes mellitus is one of the most common medical complication and a metabolic disorder that occurs during pregnancy. The essential components of humoral immunity are complement and circulating immunoglobulin. Immunoglobulin (Ig),is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to identify and neutralize pathogens such as bacteria and viruses. The complement system, a complex protein network initially identified as part of the innate immune system, is as an essential regulator of cell and tissue homeostasis.. Maternal antibodies Ig G are transported across the placenta which protects the newborn. As there are only few studies in Indian literature regarding the comparison of specific serum immunoglobulin g and complement c3 levels in gestational diabetics and normal healthy pregnant women .This review is design to compare the levels of serum immunoglobulin G and complement C3 in Gestational diabetics and normal healthy pregnant woman and its complications during pregnancy.