Abstract :
Background: Menopause is associated with various hormonal changes which are accountable for the dyslipidemic pattern seen in postmenopausal women. This deranged lipid profile in postmenopausal women is indicative of their susceptibility to various cardiovascular diseases.
Aim: The aim of the study is to estimate and compare serum lipid profile and Atherogenic index of plasma (AIP) among premenopausal and postmenopausal women.
Setting & Design: A cross-sectional study was conducted at Mahavir institute of medical sciences (MIMS), Vikarabad for a period of 3 months.
Materials and Methods: Fasting samples were collected from 100 healthy female volunteers of which 50 were premenopausal women and the other 50 were postmenopausal women. Lipid profile was performed on all samples and AIP was calculated.
Stastical Analysis: Carried out in the two groups using paired t tests. Results were expressed as mean ±SD. p value of < 0>
Results: Total cholesterol (TC), Triglycerides (TAG), Low density lipoprotein (LDL-C) were statistically significantly increased in postmenopausal women as compared to premenopausal women. Atherogenic index plasma (AIP) was elevated in postmenopausal women’s group.
Conclusion: Lipid profile screening should be mandatory in postmenopausal women as the hormonal disturbances make them more vulnerable to cardiovascular diseases and its associated complications.
Keyword :
Cardiovascular diseases, Lipid profile menopause, Postmenopausal, Premenopausal.