Abstract :
Background: Urology department is a surgical specialty department which provides health care that deals with diseases of the male and female urinary tract (kidneys, ureters, bladder and urethra. It is a cross-sectional study which aims to study the Drug Utilization Evaluation in the Urology Department and to assess the individual and potential synergistic effects of medicine used. Drug Utilization Evaluation (DUE) is an ongoing, systematic quality-improvement activity that is designed to ensure the effective and appropriate use of medicines which involves monitoring of Drug dose adjustments, inappropriate duration of drug treatment, therapeutic interchange, or generic substitution which are often addressed during the duration of therapy.
Materials and Methods: It is a cross-sectional study which was carried out among 323 in-patients in a tertiary care hospital, Bangalore. After obtaining approval from the Institutional Ethics Committee SIMS & RC / EC-10/RR-07/2024-25, Patients above 18 years admitted to the urology department and diagnosed with the urological disorders were included in the study. The data were collected from the patient case profile and prescriptions and noted in a self-designed data collection form. The statistical analysis of the collected data was performed using excel and SPSS software.
Results: The study analyzed 323 urology cases, revealing a significant male predominance (67.5%) and the highest age group represented was 29–38 years (22.3%). Benign Prostate Hyperplasia (BPH) was the most common urological disorder, affecting 15.78% of patients. Out of 323 cases, 189 patients are found with co-morbidities, Type-2 Diabetes Mellitus (43.39%) and Hypertension (40.21%) were most prevalent. Patients typically stayed an average of 4.38 days in the hospital, with 79.3% reporting treatment as effective. Preoperative medications primarily included PPIs and cephalosporins, while post-operative care also emphasized PPIs. The average number of medications prescribed in Pre-operative therapy is 66.38% while in Post-operative therapy is 68.30% which indicate significant polypharmacy. Notably, 15 Drug-Drug Interactions and 17 medication errors were identified, highlighting the need for improved medication management in the study.
Conclusion: The study highlights the complexity of managing urological patients with prevalent co-morbidities like diabetes and hypertension, emphasizing the need for careful drug management due to frequent polypharmacy. Notable drug-drug interactions and adverse reactions underline the importance of personalized care and vigilant monitoring. The focus on essential medicines and effective treatments, particularly in pre- and post-operative care, demonstrates the department’s commitment to evidence-based, efficient urological care, ultimately improving patient safety and treatment outcomes.
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