Abstract :
Colorectal carcinogenesis (CRC) is a significant health issue in developing countries. It ranks as the third most common outcome of cancer death. New drugs are required to lower the prevalence of this ailment despite a multitude of therapeutic choices. As CRC develops, several signaling pathways pathways are activated. Among the important signaling pathways are the p53, Delta-Notch, Wnt/-catenin, Salvador-Warts-Hippo (SWH), and Kelch-like ECH assocd protein 1 pathways. This paper summarises the aetiology of CRC as well as the related death of cells and cell signal transduction pathways.
Keyword :
Cell signalling, Signal transduction, Colon cancer.