Abstract :
End stage Renal Disease (ESRD) represents the terminal stage of Chronic Kidney Disease (CKD) stage 5 where in there is accumulation of toxins, fluid and electrolytes which are normally excreted by the kidneys resulting in the uremic syndrome which leads to death unless the toxins are removed by renal replacement therapy, using dialysis or kidney transplantation.
Aims & Objectives: To estimate and compare the serum levels of electrolytes, calcium and phosphorus in ESRD patients before and after hemodialysis sessions.
Materials and Methods: Cross sectional study conducted on 70 ESRD diagnosed patients, aged 30-75years of either gender on maintenance Hemodialysis. Blood samples were collected before and after Hemodialysis, analysed for Serum Electrolytes by semi autoanalyser from Roche. Serum Calcium and Phosphorus using Cobas Integra 400 plus from Roche for which Internal and External Quality Assurance Programmes are maintained. The data obtained was analysed using statistical package SPSS 20 version. The parameters are compared using paired‘t’ test, the test of probability less than 0.05 (P < 0> Result: There is significant decrease in mean serum Potassium, Chloride and Phosphorus, significant increase in serum Calcium and no change in serum Sodium after hemodialysis.
Conclusion: Thus from our study we conclude that monitoring serum electrolytes, calcium and phosphorus have prognostic significance in ESRD patients undergoing hemodialysis.
Keyword :
Calcium, End stage renal disease, Hemodialysis, Phosphorus, Serum electrolytes.