A comparative study of Widal test with blood culture in the diagnosis of typhoid fever in febrile patients


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Article type :

Original Article

Author :

Pooja Choubey

Volume :

7

Issue :

2

Abstract :

Context: Typhoid fever is a major health problem in developing countries and its diagnosis on clinical ground is difficult. Diagnosis in developing countries including Madhya Pradesh is mostly done by Widal test. However, the value of the test has been debated. Hence, evaluating the result of this test is necessary for correct interpretation of the result. Aims: A comparative study of Widal test with blood culture in the diagnosis of typhoid fever in febrile patients. Settings and Design: Materials and Methods: Blood samples were collected from 62 febrile patients with symptoms clinically similar to typhoid fever and visiting red cross Hospitals at bhopal from mid May 2018 to August 2018. Blood culture was used to isolate S.typhi and S.paratyphi. Slide agglutination test and tube agglutination tests were used for the determination of antibody titer. Statistical analysis used: Data analysis by IBM SPSS Statistics 20 Results: 10 participants were females and 22 were males in blood culture and 20 were positive, 12 were negative. Total 62 cases of S. typhi were identified with the total prevalence of typhoid fever. The total number of patients who have indicative of recent infection by either of O and H antigens. Conclusions: Total 62 cases of S. Typhi or paratyphi were identify with the total prevalence of typhoid fever.Widal test is 30 patients were observed and blood culture were observed 32 patients.

Keyword :

 Widal test, Blood culture, Sensitivity, Positive predictive value, Negative predictive value.
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