Abstract :
Background: Loss or reduced of kidney function leads to acute and chronic kidney diseases. Since past decades onwards kidney diseases showed negative impact on kidney patients in short and long time. For estimating serum adiponectin, Hemoglobin and RBCs levels are useful for early diagnosis and progression of AKI and CKD.
Materials and Methods: This is the case control study was carried out the association of serum Adiponectin levels with blood count in patients with Kidney diseases and healthy controls. A total 150 subjects included in this study in that 50 Acute Kidney Injury patients, 50 Chronic Kidney Injury Patients and 50 healthy controls was included, blood and urine samples was collected from all the included subjects. The serum Adiponectin levels are estimated by ELISA, and HB, RBCs was analysed by CBC Analyser.
Results: The present study evaluates the serum levels of Adiponectin in patients with acute, chronic kidney diseases and compared with the healthy controls. Serum Adiponectin (11.89 4.95, P - 0.0001**) levels more significant elevated in two groups of acute, chronic kidney diseases and compared with the healthy controls. This study also evaluates the hemoglobin and RBCs levels in patients with acute, chronic kidney diseases and compared with the healthy controls. The statistically significant difference between the serum Adiponectin and hemoglobin and RBCs levels in patients with acute, chronic kidney diseases and compared with the healthy controls.
Conclusions: This study suggesting that the serum Adiponectin and hemoglobin and RBCs levels useful for early detection of acute, chronic kidney diseases. To frequent monitoring serum Adiponectin and hemoglobin and RBCs levels may be useful for further complications.
Keyword :
AKI, CKD, Serum Adiponectin, Hemoglobin, RBCs.