A Study of Acute Normovolemic Haemodilution and Autologous Blood Transfusion


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Volume :

3

Issue :

2

Abstract :

Background: Autologous transfusion has advantage over homologous blood transfusion. With autologous transfusion there is avoidance of complications associated with allogenic transfusion and conservation of blood resources. Aim: To study the advantages of autologous blood transfusion in comparison with homologous blood transfusion. It is also intended to know the fall of the haematocrit levels both in Autologous blood re-infusion and homologous blood transfusion cases. It is also aimed to study the advantages of acute normovolemic haemodilution. Methods: 50 patients undergoing elective orthopaedic surgical procedures were studied and compared with 50 control patients. The study group undergoing haemodilution with 3.5% polygeline (haemaccel) and autologous blood transfusion, and the control group which received homologous blood transfusion were included in this work. Hematocrit was measured preoperatively, intraoperatively and twenty four hours after reinfusion of blood for autologous transfusion group and preoperatively and twenty four hours after surgery for homologous group. Postoperatively all the patients were closely observed for vitals and any collection of blood via drain. All the complications were noted. Results: In the study group it was observed that the haematocrit levels maintained well above safety margin levels. Conclusion: Acute normovolemic haemodilution improved tissue oxygen perfusion and micro circulation by lowering the blood viscosity. And autologous blood transfusion eliminated the blood transfusion reactions and transmission of diseases while maintaining haematorit above safe levels

Keyword :

Autologous transfusion, homologous transfusion, acute normovolemic haemodilution, haematocrit
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