Abstract :
Abiraterone acetate is specified for the treatment of prostate cancer. Two new simple spectrophotometric
techniques have been established for the assay of Abiraterone acetate in pharmaceutical dosage forms. Abiraterone
acetate shows linearity 1-100 µg/mL in methanol (λmax 248 nm); y = 0.0251x + 0.0373 (Method A) and 5-100 µg/mL
in HCl. (Method B) (λmax 240 nm); y = 0.0276x - 0.0236 and the two methods are validated.
Keyword :
Abiraterone acetate, Spectrophotometry, validation, Methanol, Hydrochloric acid.