Article PDF :

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Article type :

Review Article

Author :

Gaurav Verma, Amanpreet Kaur, Gaganjit Kaur, Mgbambouo Sodetou, Priyanka Kashyap, Qaisar Farooq, Bhumika Sharma, Gaurav Verma, Amanpreet Kaur, Gaganjit Kaur, Mgbambouo Sodetou, Priyanka Kashyap, Qaisar Farooq, Bhumika Sharma, Gaurav Verma, Amanpreet Kaur, Gaganjit Kaur, Mgbambouo Sodetou, Priyanka Kashyap, Qaisar Farooq, Bhumika Sharma

Volume :

8

Issue :

3

Abstract :

Inflammation is a fundamental biological response to harmful stimuli playing a crucial role in the body’s defense mechanisms against pathogens, toxins and injuries. While acute inflammation is a protective response that aids in tissue repair chronic inflammation ac led to long-term health issues such as arthritis, cardiovascular disease and cancer. The management of inflammation is essential for maintaining overall health and anti-inflammatory agents are pivotal in modulating the inflammatory response. Although conventional anti-inflammatory drugs like NSAIDs and corticosteroids are effective heir side effects have spurred interest in natural alternatives. Among these honey stands out due to its rich composition of bioactive compounds, including phenolic acids, flavonoids, enzymes and antioxidants, which contribute to its anti-inflammatory properties.The mechanisms include modulation of pro-inflammatory cytokines, inhibition of NF-?B and other inflammatory pathways, antioxidant activity and regulation of immune cell responses. Various types of honey such as Manuka, buckwheat and acacia honey along with regional varieties are examined for their distinct anti-inflammatory effects. Additionally, the therapeutic applications of honey in managing autoimmune disorders, chronic inflammatory conditions, respiratory infections and wound healing are discussed. The review addresses factors affecting honey’s anti-inflammatory potency, quality control, potential limitations and future research directions highlighting its promise as a natural therapeutic agent.