Abstract :
Introduction:A. baumannii is a Gram-negative, lactose-nonfermenting, oxidase-negative nosocomial pathogen. A. baumannii is one of the ESKAPE organisms that pose a global threat to humans due to constantly increasing resistance and limited treatment options. The aim of this study was to explore the distribution of sequence types (STs) among A. baumannii isolates from our tertiary care hospital, their epidemiological significance, and relationship with global trends.Materials and Methods: A total of 59 MDRAB isolates, obtained from blood and respiratory samples of VAP patients, were included in the study. The isolates were identified using VITEK2 and MALDI-TOF MS further confirmed by WGS. MLST was performed on the isolates using a bioinformatics tool to determine their sequence types.Result: Out of 59 isolates of A. baumannii, ST2 was found in 33 (55.9%), ST10 in 21 (35.6%), and ST10*, ST25, ST525, ST575 and an unknown ST were found in single isolates.Conclusion: Our findings indicate that ST2 and ST10 sequence types are predominant in A. baumannii in our ICUs.
Keyword :
A. baumannii, Sequence type, Ventilator associated pneumonia