Abstract :
Ankylosing Spondylitis (AS) is a chronic inflammatory disease affecting the axial skeleton, with variable involvement of peripheral joints and extraarticular structures. Akylosing spondylitis one of the types of seronegetive rheumatoid arthritis and is a common rheumatological condition. The prevalence of AS closely parallels the frequency of HLA-B27. The average global prevalence rates are estimated as 238 per 100,000 in Europe, 319 per 100,000 in North America, and 167 per 100,000 in Asia. Current options of treatment includes NSAIDS and BIOLOGICALS for both pain management and for halting the disease progression Here we are presenting 6 cases with various symptoms and signs of ankylosing spondylistis and we also like to discuss the pain management and patients response to monoclonal antibodies.
Keyword :
Akylosing spondylitis (AS), Seronegetive rheumatoid arthritis, Biologicals.