Abstract :
Background: Cervical spondylotic myelopathy (CSM) is a spinal disorder stemming from cervical spine degeneration, elevating the potential for spinal cord damage. Diffusion tensor imaging (DTI) represents an advanced MRI technique utilized to detect subtle alterations in the spinal cord induced by CSM. This paper aims to examine the function and prognostic significance of DTI in the early identification of CSM.Aims and Objectives: The principal goals and objectives of this research are outlined as follows: 1. The significance of diffusion tensor imaging in assessing initial changes in the spinal cord that T2A-MRI fails to reveal; 2. A comparison of DTI (diffusion tensor imaging) metrics (FA and ADC) with clinical symptoms (mNURICK s and mJOA scores); 3. The forecasting ability of DTI regarding postoperative outcomes in degenerative cervical spondylosis.Materials and Methods: In our investigation, we scrutinized 30 hospitalized individuals at our university-associated healthcare facility, who exhibited mild myelopathic symptoms but showed no T2-weighted MRI indicators. They were diagnosed with degenerative compressive cervical myelopathy based on DTI imaging. Patients were slated for surgical procedures via either an anterior or posterior method, with or without the incorporation of fusion or fixation apparatus. Each patient underwent DTI imaging both prior to and following the surgery. The post-operative DTI assessment analyzed fractional anisotropy (FA) and apparent diffusion coefficient (ADC). The modified Japanese Orthopaedic Association (mJOA) evaluation was administered before and after the surgery. A regression formula was developed.Results: Our analysis revealed that the FA value at the compression stage is considerably reduced compared to the non-compression stage (p=0.005), while the ADC value at the compression stage is elevated relative to the non-compression stage (p
Keyword :
Diffusion tensor imaging (DTI), Cervical spondylotic myelopathy (CSM), Fractional anisotropy (FA), Apparent diffusion coefficient (ADC), Modified japanese orthopedic association (mJOA).