Clinical profile of patients of pulmonary tuberculosis with diabetes mellitus attending tertiary care centre ofWestern India


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Article type :

Original Article

Author :

Madhulika H Singh, Jatin G Nagar, Meghna M Patel, Kiran C Rami

Volume :

15

Issue :

1

Abstract :

Background: Tuberculosis (TB) is one of the major infectious cause of mortality. Diabetes mellitus (DM) among TB patients affects clinical improvement, sputum conversion and mortality by various immunogenic mechanisms. Thus, clinical profile and radiological findings helps for better understanding of its correlation. Materials and Methods: It was single centre prospective study conducted for duration of 2 years. Seven hundred eighty eight TB patients screened for DM from which 95 patients following inclusion criteria considered for the study. The diagnosis of TB among these patients based on the clinical presentations and programmatic guidelines. Diagnosis of diabetes as per diagnostic criteria of American diabetes association. Results: Of 95 patients, 74 were male and 21 were female; majority belonged to adult and middle age group. Cough was most common presentation. Right side of lung was commonly involved, while lower zones commonly affected. Consolidation seen in majority of patients on radiological evaluation. 75.8% patients declared cured while, 3.2% patients died during treatment. Conclusion: Association of TB-DM is more common in males. Proper glycemic control helps in overall improvement and clinical outcome of patients.

Keyword :

Pulmonary tuberculosis, Diabetes mellitus, Treatment