Abstract :
Background: Pre eclampsia (PE) is a defined as a clinical syndrome which involves multi-organ system and is one of the major cause of maternal and perinatal morbidity and mortality. Doppler assessment of feto-placental circulation is one of the method for evaluation of pre eclampsia, which is a non-invasive screening tool without affecting the pregnancy. In the current study, uterine artery doppler waveform is assessed. A high pulsatility index and persistent diastolic notch helps in prediction of pre eclampsia and IUGR.Aims and Objectives: 1) To assess the relation between uterine artery doppler indices (pulsatility index and diastolic notching) and maternofetal outcome of pregnancy. 2) To assess the sensitivity and specificity of uterine artery doppler indices in diagnosis of pre eclampsia.Methodology: 82 antenatal women of between 11 and 14 weeks of gestation were selected after considering inclusion and exclusion criteria. Women booking to antenatal care will be subjected to uterine artery Doppler scan between 11 and 14 weeks of gestation. The bilateral uterine artery doppler indices assessed i.e., pulsatility index, diastolic notching. All patients are assessed for fetomaternal outcome.Results: Out of 82 women, 19.5% of women developed PE. In the current study 14.6% of women had pathological uterine artery PI in those 66.7% developed pre eclampsia and 16.66% delivered FGR babies.7.3% of women had diastolic notching in those 33.3% had pre eclampsia and 16.66% delivered FGR babies. Uterine artery doppler pulsatility index has sensitivity of 50%, specificity of 93.94%, PPV of 66.67% and NPV of 88.57%.Conclusion: Thus high uterine artery Pulsatility Index and persistent diastolic notching in doppler waveform at between 11 and 14 weeks of gestation has shown to predict pre eclampsia which is non-invasive and cost effective test.
Keyword :
Pre eclampsia, FGR, Pulsatility Index, Diastolic notch.