Abstract :
Posterior reversible encephalopathy syndrome (PRES) is a rare, neurological disorder characterized by visual disturbances, altered mental status, seizures, and radiographic evidence of ‘cacogenic’ cerebral edema. It is most often associated with hypertensive crises, renal failure, and immunosuppressive therapies, especially Calcineurin Inhibitors. PRES is a treatable condition with favorable prognosis, if recognized early. It typically presents with headache, seizures, confusion, and visual disturbances like blurred vision or cortical blindness. Symptoms develop rapidly and are often reversible with early treatment. We report a rare case of Mycophenolate Mofetil - induced PRES in a 43-year-old male patient following allogeneic stem cell transplantation for very severe aplastic anemia.
Keyword :
PRES, Mycophenolate Mofetil, Aplastic Anemia, Allogeneic Stem Cell Transplantation, Neurotoxicity, Immunosuppression.