Systemic lupus erythematosus and its impact on eye


Article PDF :

Veiw Full Text PDF

Article type :

Review Article

Author :

Shinisha Paul Bravian, Bravian Samvict Devadas, Adnan D Matheen, Premnath Gnaneswaran, Mohan Rao V R

Volume :

11

Issue :

4

Abstract :

Systemic lupus erythematosus (SLE) is an autoimmune condition that affects the body's own tissues by identifying as foreign pathogens. It is characterized by multisystem involvement and can affect every organ, including the eyes. Limited data is available on the prevalence of SLE due to its similarity to other various autoimmune disorders and only a few genetic factors are known to be associated with the development of the disease. SLE can present as fatigue, malaise, loss of appetite, weight loss and fever followed by development of joint pain which affects the same joints on both the sides of the body. The characteristic butterfly rash - a flat red rash on the cheeks and bridge of the nose is significant for SLE. Around 40% of patients with SLE present with ocular complaints ranging from mild irritation to optic neuropathy or SLE retinopathy to severe sight threatening complications. Ocular findings can be the early presenting feature of SLE and it can reflect the underlying systemic involvement. Prompt diagnosis by the Ophthalmologist is crucial to avoid permanent visual loss. This article emphazises the significance of collaborative approach between the Ophthalmologists, General Physicians and Rheumatologist for proper identification and treatment of the disease.

Keyword :

Systemic lupus erythematosus, Malar rash, Retinopathy, Intra vitreal injection, Vitreous haemorrhage.