Abstract :
Background: Diabetes mellitus–related metabolic alterations compromise corneal endothelial integrity and reduce its functional reserve, making diabetic eyes particularly susceptible to endothelial cell loss and morphological changes during phacoemulsification. This study evaluates these specular microscopy parameters in North Indian type?II diabetics versus non?diabetic controls to elucidate the impact of diabetes on postoperative endothelial health.Aim and Objectives: To assess and compare the endothelial cell changes after Phacoemulsification with PCIOL in type II diabetic patients versus age group matched non-diabetic patients.Materials and Methods: This comparative prospective observational follow-up study included 50 diabetic patients and 50 control patients without diabetes who underwent phacoemulsification with PCIOL. Preoperative, one day, one week, one month and three months post-surgery assessments of corneal endothelial cell changes were done using specular microscopy.The software used for the statistical analysis was SPSS (statistical package for social sciences) version 25.0 and MedCalc software. The quantitative variables in both groups were expressed as mean ± SD and compared using STUDENT T test. The p-value was taken significant when less than 0.05 (p
Keyword :
Phacoemulsification, Corneal endothelium, Diabetes mellitus, Central corneal thickness, Endothelial cell density.