A cross-sectional analytical study to assess the correlation of myopia with ganglion cell complex and retinal nerve fibre layer thickness


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Article type :

Original Article

Author :

Ishwari Suhas Karve, Shubha Nagpal, Deepa Muzumdar

Volume :

11

Issue :

3

Abstract :

Purpose: To evaluate the correlation between retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness in varying grades of myopia and emmetropia, and assess their reliability as diagnostic markers for glaucoma in myopic individuals using optical coherence tomography (OCT).Materials and Methods: This cross-sectional study, conducted at Bharati Vidyapeeth Medical College, Pune, India (November 2022–January 2024), included 148 eyes from 59 myopic patients and 15 emmetropic controls. Participants underwent comprehensive ophthalmological examinations, including OCT scans to measure RNFL and GCC thickness. Myopes were categorized by spherical equivalent (Group A1: -6D) and axial length (Group B1: 24mm). Statistical analyses included Paired-T tests, ANOVA, and Pearson correlation tests (P

Keyword :

Myopia, Retinal nerve fibre layer, Ganglion cell complex, Glaucoma, Spherical equivalent, Axial length.