Abstract :
Background: Breast cancer survivors (BCS) often face persistent psychological and physical challenges posttreatment. Mindfulness-Based Stress Reduction (MBSR) has shown promise in alleviating these symptoms, but the mechanisms underlying its effectiveness remain unclear. This study examined whether mindfulness and fear of cancer recurrence (FOR) mediate the effects of MBSR for BCS (MBSR [BC]) on psychological and physical outcomes. Methods: A randomized controlled trial (RCT) was conducted with 160 BCS (stage 0-III, within 18 months post-treatment). Participants were assigned to an 8-week MBSR (BC) program (n=80) or usual care (UC; n=80). Outcomes included perceived stress (PSS), FOR (FCRI), anxiety/depression (HADS), fatigue (FSI), and sleep disturbance (PSQI), measured at baseline (T1), post-intervention (T2), and 12-week follow-up (T3). Mediation analysis tested mindfulness (FFMQ) and FOR as mediators. Results: The MBSR (BC) group showed significant improvements in all outcomes compared to UC (p
Keyword :
Mindfulness, Fear of recurrence, Breast cancer survivors, Stress reduction, Mediation analysis