Article type :
Review Article
Author :
Abin Holla, Upender Wali, Abdullah Al-Mujaini
Volume :
3
Issue :
3
Abstract :
Immunoglobulin G4 related orbital disease is a systemic fibro-inflammatory disorders with a generalized form of clinical manifestations. Although it has a wide spectrum of various pathologies that may affect distant organs as well, there is no single clinical or pathological feature which can be diagnostic. Careful clinicopathological correlation is probably the mainstay of early diagnosis which is so important in preventing severe organ damage. Steroid is effective in managing these cases, but for those patients who are steroid resistant or dependent rituximab appears to be very efficient.