Abstract :
The study was aimed to evaluate insulin resistance and b cell function as prognostic indicator in multi organ dysfunction in septicemia. A case control follow up study consisting of 50 non diabetic patients of septicemia with multi organ dysfunction (MODS) and 50 control participants were enrolled by simple random sampling, excluding the ones not met inclusion criteria. The eligible individuals were evaluated for haematological investigation, renal function tests, serum bicarbonate, fasting blood glucose and serum insulin levels at the point of entry, 3rd day and 7th day of admission. Homa IR and Homab cell function were computed using fasting blood glucose and insulin levels. These prognostic dependent variables were compared with independent variables by the student t-test and odds ratio for assessing the mortality and severity among study participants. Study cases had a statistically significant (p
Keyword :
Septicemia, MODS, Insulin resistance, b cell function, Prognosis