Herbal phytosomal gels: Benefits, challenges, and future directions: A review


Article PDF :

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Article type :

Review Article

Author :

Abhishek Mohare, Vijaykumar Meti, Ashwini Guddad, Harish K H, Fatima Dasankoppa

Volume :

10

Issue :

1

Abstract :

The growing interest in herbal medicine has led to significant advancements in drug delivery, particularly with the development of phytosomal gels. These formulations combine herbal extracts with phospholipids to enhance the solubility, stability, and absorption of beneficial plant compounds, thereby improving their effectiveness when applied to the skin or absorbed into the body. Phytosomal technology forms a protective complex around herbal compounds, facilitating better absorption and ensuring prolonged therapeutic effects. This article explores the formulation, working mechanism, and applications of phytosomal gels in medicine and skincare. It also highlights essential quality control measures for ensuring safety and effectiveness, along with the challenges associated with these formulations and potential strategies to overcome them. Despite their advantages, phytosomal gels still face several challenges. Stability concerns, high manufacturing costs, and stringent regulatory guidelines pose significant barriers to large-scale production and commercialization. To address these challenges, researchers must refine formulation techniques, reduce production costs, and streamline regulatory approval processes. Future research should focus on scientifically validating the benefits of phytosomal gels while ensuring compliance with safety standards. Enhancing affordability and maintaining high quality will improve accessibility and adoption. As interest in natural remedies continues to grow, phytosomal gels have the potential to revolutionize medicine and skincare by integrating traditional herbal knowledge with modern scientific advancements for better therapeutic outcomes.

Keyword :

Phytosomal technology, Bioavailability enhancement, Herbal drug delivery, Formulation challenges, Therapeutic & cosmetic applications.