Role of Serum CPK and Serum Magnesium Level as a Predictor of Impending Intermediate Syndrome in Patients of OP Poisoning


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Article type :

Original Article

Author :

Singla Rahul, Singh Veer B., Meena Babu L., Kumar Harish, Kumar Deepak, Sidana Shivani, Chandra Subh

Volume :

2

Issue :

1

Abstract :

Introduction: Organophosphorus poisoning is one of the most common and deadliest poisoning especially in country like India. The intermediate syndrome occurred after the acute cholinergic syndrome but before organophosphate-induced delayed Polyneuropathy is characterised by the weakness of the muscles of respiration and of proximal limb muscles. Early identification can reduce morbidity and mortality. Aim: To assess importance of serum CPK and serum Magnesium level in patients of OP poisoning as marker OP intermediate syndrome. Material method: This was cross sectional study in PBM hospital over 93 patients over a period of 1 year. Serum CPK and magnesium level were assessed on admission and day 5 and were compared in patients who developed and didn’t intermediate syndrome. Result: Thus, CPK level on day 1 as well as day 5 but not magnesium can be used as a predictor for the intermediate syndrome. Key words: CPK (creatinine Pospho-kinase), Intermediate syndrome, Magnesium, Organophosphorus poisoning