Abstract :
Introduction: This case report documents a rare instance of ossifying fibromyxoid tumor (OFMT), a soft tissue tumor with uncertain differentiation, in a 79-year-old female. The patient presented with a progressive, painless swelling in the posterior right thigh. Ossifying fibromyxoid tumor (OFMT) is an uncommon soft tissue neoplasm characterized by variable malignant potential (Enzinger et al., 1989). With fewer than 300 reported cases, OFMT primarily affects adults, with a slight male predilection.
Case Report: A 79-year-old female presented with a 12-month history of progressive, painless swelling in the posterior right thigh, measuring 12 x 10 cm. Diagnostic Evaluation:- Fine needle aspiration cytology (FNAC): Suggested epidermal inclusion cyst. Radiographic examination: Soft tissue swelling with focal calcification and intact cortical bone. Surgical excision was performed, and histopathological examination revealed a capsulated tumor comprising epithelioid cells within a fibromyxoid matrix, surrounded by woven and lamellar bone. Immunohistochemical Analysis: - Desmin: Moderately positive and S-100: Positive. The histopathological and immunohistochemical findings confirmed the diagnosis of OFMT. This case highlights the importance of considering OFMT in the differential diagnosis of soft tissue tumors.
This case report is presented for its rarity.
Keyword :
">