Abstract :
Introduction: Metastasis of Gall Bladder Carcinoma (GBC) is very uncommon, aggressive and fatal
cancer. World wide incidence rate reported as
in women than men, older age more affected and coexisting Gall stonesare seen in majority cases. Because
of vague symptoms at early stage tumour will not be encountered, most of the patients present in advanced
stage, soprognosis is poor, hence Metastasis of GBC forms a diagnostic and therapeutic challenge.
Case Report: A 53 years old male, known diabetic past 10 years presented with intermittent vague
symptoms of vomiting, nausea, fever, fatigue, right upper quadrant pain since 3 months. Family history
of Gallstones and cancer was present. On examination 2-3 bilateral cervical swellings present, abdominal
examination reveals liver was palpable 4 cms below the right costal margin.
Relevant investigations done. Complete blood count & Liver function tests were abnormal.
Ultrasonography (USG) of abdomen and pelvis, USG guided FNAC of liver, CT of abdomen
and pelvis, PET scan of abdomen, Histopathological and Immunohistochemistry report of left
supraclavicularlymphnode biopsy were suggestive of metastatic adenocarcinoma of GB origin. After
appropriate staging adjuvant chemotherapy started, after third chemotherapy cycle he died of due to
metastasis of GBC, two months from his initial diagnosis.
Conclusion: In the present study patient was diagnosed in advanced stage, early diagnosis could be missed
due to vague symptoms and as GBC is uncommon entity, So proper evaluation of the patient in early stage
may prolong the survival.
Keyword :
Gall Bladder, Carcinoma.