Abstract :
Pirfenidone is a broad-spectrum antifibrotic medicine. In 2014, it was approved for the treatment of the idiopathic pulmonary fibrosis (IPF) by the U.S. Food and Drug Administration. Terizidone is WHO categorized group IV anti TB drug. It is an antibiotic effective against Mycobacterium tuberculosis and also M. avium for the treatment of tuberculosis, both pulmonary and extra pulmonary. The fundamental aim of this article to assemble all reported analytical methods for qualitative and quantitative analysis of Pirfenidone and Terizidone in pharmaceutical formulation as well as in biological fluids. It consist of Spectroscopy, high performance liquid chromatography, High performance thin layer chromatography.
Keyword :
Pirfenidone, Terizidone, Antifibrotic, Idiopathic pulmonary fibrosis, Analytical method.