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Recent innovations in glycobiology: Biochemical advances and applications


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Article type :

Review Article

Author :

Swapnil Phade, Dipali Mane, Abhijeet Survase, Pankaj Khuspe, Trushali Madhare

Volume :

12

Issue :

1

Abstract :

The study of carbohydrates and how they affect boil ogical processes, or glycobiology, has advanced significantly in recent years, transforming a number of industries, including diagnostics, biotechnology, and medicine. Advances in glycobiology have shown the intricate functions of glycans in immunological response, cellular communication, and the development of disease. In addition to improving our comprehension of basic biological processes, these advancements have created new opportunities for therapeutic therapies. Important developments include the creation of synthetic glycans for targeted drug delivery, the use of glycan arrays for high-throughput screening of glycosyl-protein interactions, and developments in glycomics technologies that allow thorough characterization of glcan structures. Furthermore, new biomarkers and therapeutic targets have been found as a result of the integration of glycobiology with genomes, proteomics, and systems biology, especially in the areas of autoimmune disorders, cancer, and infectious illnesses. The potential of glycobiology in healthcare is further demonstrated by the development of glycan-based vaccinations and glyco-engineering techniques to increase the stability and effectiveness of biologics. With an emphasis on the revolutionary effects these developments have had on drug development, illness treatment, and diagnostic tools, this review article attempts to give a broad overview of the most recent advances in glycobiology.

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