Abstract :
Introduction: Insulin resistance and secretion are highly dependent on variable influencing factors, in the developmental process of Diabetes mellitus. Growing incidence of diabetes prompt us to study the various contributing factors in the development of Diabetes mellitus in healthy individuals.
Objective: To study the relationship associated between anthropometric measurements, plasma lipids, glycemic indices, thyroid stimulating hormone with Insulin resistance and secretion in healthy individuals.
Materials and Methods: A cross-sectional study was conducted in normal healthy individuals, from general population.(n=142).Body mass index, body fat, were measured, Glycemic indices, fasting glucose, post prondial glucose, Glycated hemoglobin, fasting insulin levels, Thyroid stimulating hormone, fasting lipid profile were analysed.
Result: Insulin resistance (HOMA IR) is positively correlated with Glycemic indices (FBS, PPBG, HbA1C) P
Keyword :
FBS Fasting blood sugar, HbA1C Glycated Haemoglobin, HOMA IR Homeostatic Model Assessment –Insulin Resistance, HOMA-B Homeostatic Model Assessment- Beta cell secretion, TSH Thyroid Stimulating Hormone, PPBG – Post Prondial Blood Glucose.