Abstract :
Introduction: Vitamin D deficiency has been shown to be associated with autoimmune diseases, which is a controversial finding in various previous studies. Moreover there are limited studies done on serum vitamin D and its association with rheumatoid arthritis in Indian population. Therefore the present study was designed to study the level of vitamin D in patients with rheumatoid arthritis and to compare it with healthy controls.
Materials and Methods: The study included 40 patients diagnosed for rheumatoid arthritis (RA) and 40 age and sex matched healthy controls who were willing to participate in the study from the department of orthopaedics and General medicine. After obtaining the written informed consent from all the participants, 2 ml of blood was collected in a plain vacutainer for the estimation of vitamin D by chemi-luminescent method.
Results: The cut off values of 25-OH vitamin D level, being 30ng/ml as normal. There was neither any statistical difference in the vitamin D levels nor in the vitamin D deficiency level (
Keyword :
Rheumatoid arthritis, Auto-immune disease, Chemi-luminescent method, Vitamin D