Estimation of Adenosine deaminase and proteinase inhibitory activity and their correlation with tuberculous effusion and other pleural effusion cases


Article PDF :

Veiw Full Text PDF

Article type :

Original Article

Author :

Beenakumar K., M.R.Laveesh, NVU Warrier, Parvathi K., Jose Raj M.G

Volume :

3

Issue :

1

Abstract :

Introduction: Diagnosis of tuberculous effusion is difficult with the conventional, bacteriological, cytological and histopathological methods in our country. Adenosine deaminase, serum proteins, phospholipids show marked variation in tuberculous exudates. Material and Methods: Twenty cases of pulmonary tuberculosis, 10 cases of malignant effusions and 8 cases of other para-pneumonic effusions visiting a tertiary care hospital were included in this study. After collecting blood and pleural fluid samples, Adenosine deaminase, Alpha-1 antitrypsin l, proteinase inhibitor activity, total lipid levels, phospholipid and Lipase activity were estimated. Observation and results: Serum ADA levels in tuberculous effusion was 21.8 9.8 U/L(10-45.08) P

Keyword :

ADA Adenosine deaminase, ?1antitrypsin, Tuberculosis, Proteinase inhibitory activity, Lipase, Phospholipid