Author :
Kavitha M M, Chandrashekharayya S H, Sangappa V Kashinakunti, Manjula R, Gurupadappa K
Volume :
3
Issue :
1
Abstract :
Background: Hypothyroidism is associated with dyslipidemia. The present study was conducted to assess the relation between hypothyroidism and lipid parameters and lipid ratios. It is also done to assess the severity of hypothyroidism on lipid parameters.
Methods: Study comprises of 120 participants were divided into four groups depending on TSH levels, each group comprising of 30 participants. Group-1 euthyroid as controls, group-2 hypothyroid patients with TSH levels between 6-20 mIU/mL, group-3 TSH levels between 21-50 mIU/mL and group-4 consists of hypothyroid patients with TSH levels of > 50 mIU/mL. Fasting venous blood was collected from all the participants and analyzed for estimation of thyroid profile and lipid profile. Lipid ratios were calculated.
Results: There was significant (p < 0.05) increase in total cholesterol, triglycerides, LDL-C and HDL-C in all the groups compared to group-1 i.e. controls. There was significant increase (p