Author :
Rahul M. H, Deepa K, Varun Reddy, Sudhir, Shubha Jayaram
Volume :
2
Issue :
4
Abstract :
Introduction: Obesity is the leading cause for cardiovascular disease in the world. Cystatin C is a novel marker of cardiovascular disease and atherogenic indices which is used as an index for cardiac risk stratification. The objective of the study was to estimate the Cystatin C levels in non-obese and obese individuals aged between 18-39 years and to compare the levels of Cystatin C among these individuals. The study was also done with an objective to know the association of Cystatin C with atherogenic indices.
Methodology: The subjects were selected from healthy volunteers of Mysore aged between 18-39 years of either sex. They were grouped into two groups based on their BMI. Each group had sample size of 60. Sample were collected in fasting state and analyzed for Total Cholesterol, Triglyceride, LDL-Cholesterol & HDL cholesterol by enzymatic method and Cystatin-C by immune-turbidimetric method using Randox auto-analyzer.
Results and Interpretation: The mean serum Cystatin C level in non obese group was 0.7±0.03 mg/L, and in Obese group 1.15±0.09 mg/L (p value