Author :
Savitha Jagannath, Meera. S, Shubha Jayaram, Sahithya C. S.
Volume :
1
Issue :
1
Abstract :
Psoriasis is a chronic, inflammatory skin disease characterized by epidermal hyper proliferation, differentiation and lymphocytic infiltration predominantly of T lymphocytes. Evidence have shown that psoriasis is an independent risk factor for cardiovascular diseases. hs-CRP is an acute phase reactant and best biomarker of inflammation that has been associated with cardiovascular disease(CVD) risk .Hence this study was undertaken to evaluate hs-CRP, lipid profile and Novel Lipid Indices in psoriatic patients.
Materials and Methods: The study group consisted of 47 psoriasis cases and 47 healthy controls. PASI (Psoriasis Area and Severity Index) Score was done to assess severity of Psoriasis. Lipid profile (Total Cholesterol, Triglycerides, LDL and HDL) was measured in fully automated analyser. hs-CRP was measured by immuno turbidimetric method. Statistical analysis was done by using SPSS-16 version. Results: Statistically significant (p