Abstract :
Background: Diabetes Mellitus (DM), a chronic metabolic disorder consistently identified by the state of hyperglycaemia. It results due to inability of the body to synthesize insulin, resistance to the action of insulin or both.
Aim: To compare the occurrence of urinary tract infection amongst patients of Type 2 DM receiving Dapagliflozin monotherapy versus Dapagliflozin and Sitagliptin combination therapy.
Objectives: 1) To study the occurrence of urinary tract infection in patients receiving Dapagliflozin monotherapy. 2) To study the occurrence of urinary tract infection in patients receiving Dapagliflozin and Sitagliptin combination therapy 3) To compare the occurrence of urinary tract infection in both groups 4) To study if combination therapy reduces the occurrence of UTI
Materials and Methods: The study was conducted after approval from the Institutional Ethics Committee.
Study design, type, site, duration, number of subjects, and inclusion and exclusion criteria were required and data collected.
Results: This study helped us to study the most commonly reported ADR with the use of newer anti- diabetic drugs.
Conclusion: No significant difference were noted in the incidence of UTI in both groups, showing that combination therapy did not offer any benefit in reducing the risk of UTI.
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