Abstract :
Various novel quinazolinones and quinazolidine dione derivatives were prepared by using anthranilic acid. Anthranilic acid was synthesized by treating phthalimide with sodium hypobromide solution. The synthesized anthranilic acid was treated with urea, thiourea, acetamide and benzamide to give corresponding titled compounds in good yields. The synthesized compounds were characterized by physical properties and spectral studies (IR, 1H-NMR) and tested for antimicrobial activity.
Keyword :
Anthranilic acid, Urea, Thiourea, Benzamide, Quinqzolinones and Quinazolidine diones