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Dedifferentiated endometrial carcinoma – unveiling the complexities of an aggressive tumour


Article PDF :

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Article type :

Case Report

Author :

Shemeera Saidalavi Vellolipadikkal*, Lillykutty Pothen, Nikita James, Rebecca Mathews, Meeta Thomas

Volume :

12

Issue :

1

Abstract :

Uterine corpus tumours represent the most common gynaecological malignancies, with their pathological characteristics largely well-documented. However, dedifferentiated endometrial carcinoma (DEC) remains a subject requiring extensive research to establish appropriate management guidelines. Here, we present two cases of DEC, highlighting its morphological and immunohistochemical features that may aid in differential diagnosis. Recognizing this subtype is crucial, as it is associated with worse clinical outcomes and a poorer prognosis compared to high-grade endometrioid carcinoma.

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